Accuracy of phylogeny-based topological dating of human duplicates. Each line represents the use of different adjacency thresholds (number of genes allowed between the syntenic pair of paralogs) to detect PAP cases. Y-axis indicates the percentage of PAP cases for which topological dating was consistent, that is, cases in which paralogs within a same PAP were mapped to the same evolutionary period. X-axis represent different branch support thresholds (aLRT support values) that is used to detect duplication events in phylogenetic trees. The number of PAP cases at each window size and branch support value are as follows: window size 0: 326, 254, 168, 109, 46, 29; window size 5: 1542, 1170, 694, 412, 178, 117; window size 10: 2327, 1750, 965, 558, 230, 150; and window size 20: 3504, 2566, 1401, 792, 310, 193.