mRNA expression levels of IDH-mutant glioma. Top: Boxplots log₂ normalized expression values of VIM (left) and HIP1R (right) originating from the TCGA database. High levels of VIM coding mRNA in IDH-mutant glioma without 1p/19 codeletion and low levels of VIM in glioma with 1p/19q codeletion are observed. Vice versa high levels of HIP1R coding mR NA are found in 1p/19q codeleted glioma and low levels of HIP1R in glioma without 1p/19 codeletion. Bottom: Heatmap showing Z-scored expression values, samples were ordered by their 1p/19q status. Pairwise comparison of z-scored expression values demonstrates that 1p/19q codeleted glioma exhibiting low levels of VIM and high levels of HIP1R. In contrast glioma without 1p/19q codeletion exhibit high levels of VIM and lower levels of HIP1R.