Changes from baseline to 1 month and final visits for serum concentrations of (A) procollagen type-III N-terminal pro-peptide (PIIINP); (B) procollagen type-III N-terminal pro-peptide for those with a baseline serum galectin above or below median; (C) procollagen type-I C-terminal pro-peptide (PICP); (D) collagen type-1 C-terminal telopeptide (CITP); (E) the ratio of procollagen type-I C-terminal pro-peptide to collagen type-1 C-terminal telopeptide; (F) Galectin-3. Data shown are mean change and standard deviation. P-values are for the comparison between intervention and control except for (B) where the P-values refer to the interaction between baseline serum galectin-3 and changes in plasma concentrations of procollagen type-III N-terminal pro-peptide. The interaction between baseline galectin-3 and change from baseline to final visit in procollagen type-III N-terminal pro-peptide was the primary endpoint of the trial (P = 0.947 for the interaction).