Flowchart depicting COVID-19 treatment eligibility criteria used in outpatient clinics of Boston Medical Center. OP indicates outpatient. aUnvaccinated, immunosuppression (including HIV/AIDS, T- or B-cell malignancy, hematologic malignancy, use of biologics), sickle cell disease, 65 years of age or older, diabetes mellitus, chronic kidney disease, chronic liver disease, cardiovascular disease, neurological disorder, chronic lung disease, substance use disorder, mental health disorders, smoker, pregnancy, body mass index of >30, stroke and/or cerebrovascular accident, or tuberculosis.bMolnupiravir may be considered in patients who cannot receive Paxlovid (eg, those with estimated glomerular filtration rate of <30 mL/min or significant drug-drug interactions) and/or those who do not want to receive intravenous therapy.