Cntnap2  ^−/− neurons are synaptically comparable to wildtype neurons. (A) Sample recording trace of spontaneous EPSCs from the auditory cortex of an adult wildtype rat with the (B) mean frequency and (C) mean amplitudes. (D) Representative recording areas including the primary auditory cortex (A1) in the rat, accompanied by the positions of the recording and stimulating electrodes in layers 2/3 and layers 5/6, respectively. (E) Sample traces of paired pulse evoked EPSCs from a wildtype rat at various ISIs, vertical lines represent stimulation pulses, and (F) paired-pulse ratios (amplitude of the second EPSC divided by first EPSC). All data are represented as mean ± SE (B, C: wildtype n = 19 cells, Cntnap2^−/−  n = 13 cells; F: wildtype n = 12 cells, Cntnap2^−/−  n = 6 cells). ^*P <0.05.