Responses to acoustic stimuli from central auditory areas in rats. (A) BAEP from a single rat elicited by the presentation of click stimuli (90 dB SPL); averaged CAEP from a representative multiunit cluster elicited by the presentation of a 50 ms noise burst stimuli (90 dB SPL); cortical spiking activity from a representative multiunit cluster elicited by the presentation of a 50 ms noise burst stimulus or from a six-pulse train composed of 25 ms noise bursts presented at six different repetition rates (90 dB SPL). Dot raster plot (dot = 1 spike; row = 1 trial) and/or line peristimulus time histogram (PSTH; 2 ms bins) shown. (B) Representative recording penetration in the primary auditory cortex (A1) in the rat, accompanied by schematics of the locations of electrode penetrations reconstructed from histological sections for each of the rats that underwent in vivo electrophysiological recordings (wildtype rats, n = 7 and Cntnap2−/− rats, n = 8). Electrodes were advanced into the cortex falling between 3.72 and 4.56 mm caudal to bregma.
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