Joint analysis of all immune cells across HCA with Fugue. (A) UMAP plot of the 17 immune cell types inferred from Fugue. Cells are colored by cell type labels. (B) Dot plot showing cell type markers across cell clusters. The size of each circle reflects the percentage of cells in a cluster where the gene is detected, and the color intensity reflects the average expression level within each cluster. (C–D) Violin plot deciphering expression levels of cell type markers for HSCs (C) and NK cells (D) across HCA cohorts. Cohorts with >1000 cells in each cluster were displayed.