Copy number aberrations in cancer samples and adjacent mucosa of patients with PSC-IBD. Frequency plots of the copy number aberrations in 19 cancer samples of PSC-IBD-CRC (upper panel) and 15 adjacent mucosa samples (lower panel). Copy number gains (blue) and amplifications (dark blue) or losses (red) and homozygous deletions (dark red) on the different chromosomes are shown. Abbreviations: PSC-IBD, concomitant primary sclerosing cholangitis and inflammatory bowel disease; PSC-IBD-CRC, colorectal cancer associated with primary sclerosing cholangitis and inflammatory bowel disease.