Manhattan plots representing the scores of each statistic for selection tests performed on highland (A), coastal (B), and rainforest (C) populations. In red, the top 10 significant candidate regions identified in each test. H, Highlands; C, Coast; R, Rainforest. (D) Number of top signals of positive selection detected with the PBS, his, and XP-EHH statistics per each ecoregion. Genomic regions are considered under selection exclusively in an ecoregion when they are not found within the top 50 signals obtained by tests performed on other ecoregions. In brackets, total number of top 10 signals detected without filtering out those also within the top 50 of the remaining ecoregions. *Indicates that the highest scoring SNPs within a peak are in an intergenic region. *1 in (B): HLA-DRB1, HLA-DQA1, HLA-DQA2, HLA-DQB2, HLA-DOB, TAP2, PSMB8, PSMB8-AS1, TAP1, PSMB9, LOC100294145, HLA-DMB, HLA-DMA, BRD2, HLA-DOA, HLA-DPA1. *2 in (B): SSSCA1-AS1, EHBP1L1, KCNK7, MAP3K11, PCNX3, RELA, KAT5, RNASEH2C, AP5B1, MIR1234, OVOL1-AS1, OVOL1, SNX32, CFL1, MUS81, EFEMP2, FIBP.