MRI of the brain with contrast, with T1 MP-RAGE sequences shown. A, MRI of the brain obtained at the time of initial TB diagnosis, showing a 1.0 × 1.2 cm area of enhancement in the right mesial parietal lobe. B, MRI of the brain obtained at the time of re-presentation and diagnosis with CNS TB-IRIS. The previously seen area of enhancement is slightly increased in size to 1.0 × 1.3 cm, and there is new surrounding vasogenic edema, measuring 4.5 × 2.3 cm. Abbreviations: CNS, central nervous system; MRI, magnetic resonance image; TB, tuberculosis; TB-IRIS, immune reconstitution inflammatory syndrome to tuberculosis.