Model training and evaluation. (A) ROC curve of MultiDTI model by 10-fold cross-validation method. (B) ROC curve of MPNNs-CNN model by 10-fold cross-validation method. (C) Performance of the three DL-based models by 10-fold cross-validation method. (D) ROC curve of MultiDTI model on Test-78. (E) ROC curve of MPNNs-CNN model on Test-78. (F) Performance of MultiDTI and MPNNs-CNN models on Test-78.