Functional connectivity of domain-general network regions during semantic fluency. (A) Within- and between-network functional connectivity for each seed to target combination for each group. Heatmaps show t values. Thresholded t values with Meff-corrected α of 0.0018 are indicated with black boxes. (B) Effect of age on functional connectivity. There were no age differences in functional connectivity between or within networks. Heatmaps show t values with Meff-corrected α of 0.02. Significant effects are indicated with black boxes. (C) Significant two-way interactions between age and functional connectivity for response time during semantic fluency. (D) Correlation analyses between functional connectivity measures and neuropsychological factors. For within-MDN connectivity, only older adults showed a significant correlation with executive functions, while only young adults showed a significant correlation between semantic memory and between-network functional connectivity. Abbreviations: R, right hemisphere; L, left hemisphere; AG, angular gyrus; ACC, anterior cingulate cortex; Prec, precuneus.