The comparison between scHiCStackL and four methods (scHiCluster, HiCRep-MDS, Raw_PCA and Decay) is based on the |$99\%$| confidence interval of results(the whole Ramani dataset). The five methods are scHiCStackL, scHiCluster, HiCRep-MDS, Raw_PCA and Decay from left to right. The upper and lower edges indicate the maximum and minimum values of the results, respectively. The box represents the confidence interval of the results.