On sagittal FLAIR (a) a well-defined hyperintense lesion is detected in the splenium of the CLOCC; diffusion-weighted MR images (DWI) shows high signal on DWI (b) with corresponding low ADC (c), indicating diffusion restriction (arrow); the abnormality was consistent with cytotoxic lesion of the CLOCC; follow-up MRI 3 weeks later shows complete resolution of the abnormality (d–f)