Androgen receptor signaling pathway. Baseline tumor biopsies were assessed for gene differential gene expression of a defined AR signature. (A): Heatmap of gene expression of AR signature. Row orders are based on hierarchical clustering. Column orders are based on the specific response groups. (B): AR signature scores between responder and nonresponder groups. Statistics assessed by two‐tailed Mann‐Whitney test. Nonresponders (PD + SD) in red, responders (CR + PR) in blue.