FIGURE 5
Principal component analysis (PCA) of whole transcriptome gene expression in tumor tissues. (A): Heat map showing scaled expressions of top 10 genes with significantly differential expressions (false discovery rate ≤ 0.10) for responders versus nonresponders . (B): PCA diagram with type of specimen and response to treatment.
Abbreviations: CR, complete response; LN, lymph node; NR, nonresponders; PC1, principle component 1; PC2, principle component 2; PD, progressive disease; PR, partial response; Pre‐Tx, pretreatment; R, responders; SD, stable disease.
