Patient with intrahepatic cholangiocarcinoma with a single brain metastasis to the L cerebellum. Hematoxylin and eosin stains (low power [×4]) of primary liver with tumor and adjacent hepatocytes (A) and (high power [×20]) of primary liver adenocarcinoma (B). Hematoxylin and eosin stains of brain metastasis at ×4 (C) and ×20 (D), showing similar histologic features as seen in the liver.