Risk of being diagnosed with subclinical hypothyroidism (A) or subclinical hyperthyroidism (B) in relation to time of sampling. Restricted cubic spline curves with three knots of log relative odds risk of being diagnosed with subclinical hypothyroidism (SCH) (A) or subclinical hyperthyroidism (SHyper) (B) (black line) with 95% confidence intervals (grey areas) were plotted against time of sampling (24 hour clock), adjusted for age, sex, center, body mass index, smoking status, type of acute myocardial infarction (STEMI or NSTEMI), pain to sampling time, serum creatinine, thyroid peroxidase antibody levels, history of ischemic heart disease, diabetes mellitus, hypertension, cerebrovascular disease and atrial fibrillation.