LSD1 enhances the malignant potentials of PTC cells by upregulating the expression of HIF1α. (A) The expression of LSD1, HIF1α, miR-146a and GABPA in K1 cells determined by RT-qPCR. (B) The expression of LSD1, HIF1α, and GABPA in K1 cells determined by Western blot analysis. (C) The expression of EMT-related proteins E-cadherin, β-catenin, N-cadherin and Vimentin measured by Western blot assay. (D) The proliferation of K1 cells assessed by EdU labeling (× 200). (E) The migration of K1 cells assessed by scratch test. (F) The invasion of K1 cells evaluated using Transwell assay (× 200). The data in the figure were all measurement data, which were expressed by mean ± standard deviation. Data among groups were statistically analyzed by one-way ANOVA. The experiment was independently repeated 3 times. *P < 0.05.