Impact of echocardiographic factors on LA volumes. The figures show the continuous association between echocardiographic measures and LA volumes for the overall population. Specifically, they show left ventricular size (left ventricular internal diameter) and changes in LAVmax (A) and LAVmin (B), between global longitudinal strain and changes in LAVmax (C), and between left ventricular mass index and changes in LAVmin (D). All figures illustrate a linear acceleration in LA volume changes with increasing left ventricular size and mass and with deteriorating global longitudinal strain. The associations are adjusted for the respective baseline LA measure, age, and gender. LA, left atrium; LAVmax, maximal left atrial volume; LAVmin, minimal left atrial volume