TransPath-C models for Ms22q11DS and HuSZ cohorts. (A) AUC curve results for Ms22q11DS model following LOOCV. (B) Misclassification table for Ms22q11DS model following LOOCV. (C) Feature weights on sPCs used by the final Ms22q11DS SVM trained on all samples. (D) AUC curve results for HuSZ model following LOOCV. (E) Misclassification table for HuSZ model following LOOCV. (F) Feature weights on sPCs used by the final HuSZ SVM trained on all samples. (G) Loading weights of the Ms22q11DS SVM predictive sPC2. Colors in bar plots denote correlation with WT (light grey) and 22q11DS (teal) phenotypes in the Ms22q11DS cohort. (H) Loading weights of the HuSZ SVM predictive sPC8. Colors of bar plots denote correlation with Control (dark grey) and SZ (green) in the HuSZ cohort.