Working model of possible molecular mechanism of brassinazole-resistant 2 (TaBZR2)-mediated resistance and tolerance processes. The concentration of TaBZR2 in plant cells is affected by drought, and it positively regulates glutathione S-transferase 1 gene (TaGST1) expression by binding to the promoter (bent arrow) and activating transcription. As a result, drought-induced O²⁻ content is significantly reduced. Furthermore, TaBZR2 may also increase the expression of drought-related genes through other signaling pathways (Left). After Pst infection, transcription of TaBZR2 is induced and positively regulates expression of TaCht20.2 by binding to its promoter (bent arrow) and activating transcription. As a result, the chitinase activity is increased in vivo. Additionally, TaBZR2 may also increase the expression of pathogenesis-related genes (TaPRs) and increase the H₂O₂ content through other signaling pathways (Right). In short, TaBZR2 improves wheat tolerance to drought and resistance to Pst infection. The left panel has been reported. Solid arrows indicate direct effects and dotted arrows indicate indirect effects.