Absolute and relative change from baseline in sUA levels at each weekly visit. (A) Mean absolute sUA change from baseline. (B) Mean relative sUA change from baseline. At week 1, SHR4640 and placebo were received at 1 mg dose and benzbromarone at 25 mg dose. Since week 2, SHR4640, placebo and benzbromarone were added to pre-set dose. Values are mean (s.d.). sUA: serum uric acid.