Figure 4
![Head-to-head comparison of [18F]PI-2620 and [18F]PM-PBB3 in patients with PSP-CBS (#52). (A) [18F]PI-2620 and [18F]PM-PBB3 imaging in subject #52 representative of range of tracer binding. Transaxial and coronal [18F]PI-2620 images adjacent to same-slice [18F]PM-PBB3 images are shown. Red arrowheads indicate positive retention of both [18F]PI-2620 and [18F]PM-PBB3 (globus pallidus and substantia nigra). Blue arrowheads indicate positive [18F]PM-PBB3 retention, but weak [18F]PI-2620 (thalamus, frontal gyrus and subthalamic nucleus). (B) Plot of SUVR for [18F]PI-2620 and [18F]PM-PBB3 in matching ROIs. P-values for Spearman correlation test.](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/braincomms/3/4/10.1093_braincomms_fcab190/1/fcab190f4.jpeg?Expires=1749432660&Signature=01GYCcsDL6LZJnUdQdgiNSyP5klxwST~OFd3QTwDLhGnXw2daweLUeSgMd~2lF30c~BDajUI8WFdijzhFs5MzpPaY0ByL5g7WKP~VozaEAWUKxabnEi8EiugN46BUydc2Q4sYxBmXcS2ILbImSR~Eq3W3ROVuK1ljPaZTX9e5ijtCSPmxXRSk2fxYA7w94gC1GeBOxYUeFQg9LW76vXfj5CwHi8qHizQbE2doSLuc0fiZuxjNBZVMn~Nr1Gp5~1hsB87pUh~S7XglfrxBt1ZavDwezXLLRVlrVO4XkkoR~7dopWmEh6e8MdxYGQ0A88L9iLghvU4rjT9OOCYPmYaGw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Head-to-head comparison of [18F]PI-2620 and [18F]PM-PBB3 in patients with PSP-CBS (#52). (A) [18F]PI-2620 and [18F]PM-PBB3 imaging in subject #52 representative of range of tracer binding. Transaxial and coronal [18F]PI-2620 images adjacent to same-slice [18F]PM-PBB3 images are shown. Red arrowheads indicate positive retention of both [18F]PI-2620 and [18F]PM-PBB3 (globus pallidus and substantia nigra). Blue arrowheads indicate positive [18F]PM-PBB3 retention, but weak [18F]PI-2620 (thalamus, frontal gyrus and subthalamic nucleus). (B) Plot of SUVR for [18F]PI-2620 and [18F]PM-PBB3 in matching ROIs. P-values for Spearman correlation test.
