Cardiophenome-wide analysis of variants discovered in GWAS. Coloured according to normalized CAD risk allele effect size and highlighted with significant non-normalized test P-values. Association tests were conducted for body mass index (BMI), waist to hip ratio (WHR), systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), pulse pressure (PP), central augmentation index (CAIX), central systolic blood pressure (CSBP), central diastolic blood pressure (CDBP), central mean arterial pressure (CMAP), central end-systolic pressure (CESP), central pulse pressure (CPP), subendocardial viability ratio (SERV), time to reflection (TR), brachial pulse wave velocity (BPWV), central pulse wave velocity (CPWV), left common carotid artery intima media thickness (IMTLEFT), right common carotid artery intima media thickness (IMTRIGHT), mean common carotid artery diameter (DIAMETER), cholesterol concentration (CHOL), low-density lipoprotein concentration (LDL), log-transformed triglyceride concentration (TG), high-density lipoprotein concentration (HDL), weighted mean HbA1c level (HBA1C), leucocyte concentration (LEUK), log-transformed C-reactive protein concentration (CRP), and log-transformed annual antibiotic purchases (INFECTIONS).