Average annual percent change of metastatic disease incidence rates by cancer site: Surveillance, Epidemiology, and End Results Program (2000-2016). Bone, rhabdomyosarcoma, and uterus not displayed because of insufficient cases (see the Methods section). Error bars indicate 95% confidence intervals. AYA = adolescent and young adult; MA = middle-aged adult; OA = older adult; STS = soft tissue sarcoma (excluding rhabdomyosarcoma and Kaposi sarcoma).