Figure 5
Predicted model of SNORD116:NHLH2 interaction. The ViennaRNA package software was used to predict the folding structure for NHLH2 3’UTR, and then the interaction with SNORD116. The miR-9-5p interaction site was identified using TargetScan. Both interactions were added to the overall structure for viewing of their relative positions on the NHLH2 3’UTR only, not to indicate whether one or both simultaneously interaction with the stem-loop structure. *indicates the site of the NHLH2 SNV used in the current study.

Predicted model of SNORD116:NHLH2 interaction. The ViennaRNA package software was used to predict the folding structure for NHLH2 3’UTR, and then the interaction with SNORD116. The miR-9-5p interaction site was identified using TargetScan. Both interactions were added to the overall structure for viewing of their relative positions on the NHLH2 3’UTR only, not to indicate whether one or both simultaneously interaction with the stem-loop structure. *indicates the site of the NHLH2 SNV used in the current study.

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