Fig. 1
(A) Improvement in survival of childhood ependymoma from 1960 to 2015 in the UK. Based on 347 retrospectively analyzed UK cases—unpublished data associated with the Ritzmann et al.’s 2020 study.2 (B) Proposed structure for a relapsed ependymoma clinical trial allowing the comparison of craniospinal and focal radiotherapy. Abbreviations: CSI, craniospinal irradiation; M0, no metastatic disease; RT, radiotherapy.

(A) Improvement in survival of childhood ependymoma from 1960 to 2015 in the UK. Based on 347 retrospectively analyzed UK cases—unpublished data associated with the Ritzmann et al.’s 2020 study.2 (B) Proposed structure for a relapsed ependymoma clinical trial allowing the comparison of craniospinal and focal radiotherapy. Abbreviations: CSI, craniospinal irradiation; M0, no metastatic disease; RT, radiotherapy.

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