Fig. 1
![Patient with a multifocal IDH-wild-type glioblastoma. The extent of increased FET uptake based on a tumor-to-background threshold of >1.6 (left image; red contour transferred onto MR images) is considerably larger than the contrast enhancement (middle image) and the extent of the signal hyperintensity on the T2-weighted MR image (right image). Abbreviations: FET, O-(2-[18F]-fluoroethyl)-l-tyrosine; IDH, isocitrate dehydrogenase.](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/neuro-oncology/23/6/10.1093_neuonc_noab013/1/noab013f0001.jpeg?Expires=1749634286&Signature=2PyzUPpMm8~EIzVpU4A1VEUsMQp-I2~Fo5hOXJCfKlgxr8wnHTq0yDE6OTyr86B4NT57ASBinnEMdlap5w~MT4hogSuBFfH5ECmCKTV4sM-LnVf75rg8g71vhrLZpBq2QeRgq~~nFzQCSUenmvdoZEEGalIrzIrMG1ZwEOe6DAsnBv9C4CXtQsMPhCALTxhezHM58N~B7cmX46C5BgzBsGz9F803TEBkbASXleCcaNerkf8BbdsfIBy0Fcg~kNj7lHk8E8cEiIC4gmSHSbZjzUXw4bh11CsAGV2E45Lo1FQPvg53IWTr-MjYSR8ctkJyYp4wV9lF47n-j-57OPuNNQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Patient with a multifocal IDH-wild-type glioblastoma. The extent of increased FET uptake based on a tumor-to-background threshold of >1.6 (left image; red contour transferred onto MR images) is considerably larger than the contrast enhancement (middle image) and the extent of the signal hyperintensity on the T2-weighted MR image (right image). Abbreviations: FET, O-(2-[18F]-fluoroethyl)-l-tyrosine; IDH, isocitrate dehydrogenase.
