Figure 5.
![7-deazaguanine derivatives can be displaced from tRNA by QTRT. Evaluation of the ability of the QTRT enzyme (100 nM) to insert either; (A) [3H] guanine (200 nM) or (B) [3H] queuine (200 nM) into tRNA (10 μM) that had been pre-charged with natural or artificial nucleobases over a period of either 30 min or (C) 24 h. Data are mean ± SD (n=3). Representative of two independent experiments.](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/nar/49/9/10.1093_nar_gkab289/1/gkab289fig5.jpeg?Expires=1749759926&Signature=IukB80KfUZgrKRi9UGpgH3FJFWqmuaJfQJyQOBkvAlJ6CkHEyiEbxqSyl1YqgWbkzDfywlzQMdpwXmmywAqfuaOO88D8yvwcgT0Okt3dTEhTOXdoPf3CQBLJ2RuQuZ-keEybVqQaiFx9HU~HncHqTog6-1le9DqBQIOyIdZB9mRV8gJPbGxF0ieZfGX8o-ZBpUzS47AjZwLlIuaC6SKWt8d1HaicEDaADWLO3-zXzVd9wOqapddesjwRYouZoo8bDFpPcuC6C2JdAzHSnSArYc6nU63A4ld5T1TVYkmLsIPSieRz-kFKG-~e65~s2qZOi9IKV7wE4-A~zzq9UMaD7w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
7-deazaguanine derivatives can be displaced from tRNA by QTRT. Evaluation of the ability of the QTRT enzyme (100 nM) to insert either; (A) [3H] guanine (200 nM) or (B) [3H] queuine (200 nM) into tRNA (10 μM) that had been pre-charged with natural or artificial nucleobases over a period of either 30 min or (C) 24 h. Data are mean ± SD (n=3). Representative of two independent experiments.
