FIGURE 5
ROC curve for three biomarkers—IgA1, Gd-IgA1 and IgA-α1-microglobulin complex—for the diagnosis of IgAN. (A) For the diagnosis of IgAN, the AUC for the IgA-α1-microglobulin complex was significantly higher than that for IgA1 {0.862 [95% confidence interval (CI) 0.807–0.917] versus 0.732 [95% CI 0.652–0.811]; P < 0.001}. (B) In addition, the AUC for the IgA-α1-microglobulin complex showed a higher tendency than that for Gd-IgA1, although statistical significance was not reached [0.862 (95% CI 0.807–0.917) versus 0.803 (95% CI 0.739–0.867); P = 0.076].

ROC curve for three biomarkers—IgA1, Gd-IgA1 and IgA-α1-microglobulin complex—for the diagnosis of IgAN. (A) For the diagnosis of IgAN, the AUC for the IgA-α1-microglobulin complex was significantly higher than that for IgA1 {0.862 [95% confidence interval (CI) 0.807–0.917] versus 0.732 [95% CI 0.652–0.811]; P < 0.001}. (B) In addition, the AUC for the IgA-α1-microglobulin complex showed a higher tendency than that for Gd-IgA1, although statistical significance was not reached [0.862 (95% CI 0.807–0.917) versus 0.803 (95% CI 0.739–0.867); P = 0.076].

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