Boxplots of TSC, ADC, and FA distributions within the mTBI and control (CTL) cohorts for the 12 ROIs. Boxplots show the 1st, 2nd (median) and 3rd quartiles (box), ±95% (whiskers), and means (*) of the TSC, ADC and FA values obtained via voxel averaging from the global WM, global cortical GM, and regional WM and GM ROIs. The boxplots exclude the three oldest mTBI patients who lack age-matched controls. The FA in frontal white matter and the TSC in the caudate were lower in mTBI compared to controls (MW test, filled diamonds: P  < 0.05). Note that nine out of 12 ROIs showed a lower median TSC in mTBI than in controls. gWM = global white matter; BCC = body of corpus callosum; GCC = genu of corpus callosum; SCC = splenium of corpus callosum; CR = corona radiata; FWM = frontal white matter; PWM = posterior white matter; gcGM = global cortical GM; CA = caudate; PA = pallidus; PU = putamen; TH = thalamus.