PDCD5 overexpression induces cell death and increased DNA damage repair. A, Representative images of stem cells and adjacent daughter cells from wild-type (WT) Col-0 and Wassilewskija (Ws), pdcd5-2, ham1ham2  RNAi, and ham1ham2  RNAi/pdcd5 mutants, and PDCD5-overexpressing plants (PDCD5 OE) that were scored for intense PI staining to count dead stem cells per root after UV-B. Arrows indicate dead cells. Bars = 50 μm. B, Number of stem cells that are dead after UV-B exposure relative to those in wild-type plants (Col-0 and Ws). Three independent transgenic lines were analyzed (PDCD5 OE-2, PDCD5 OE-11, and PDCD5 OE-12). Statistical significance was analyzed using a one-way ANOVA test at P < 0.05; differences at P < 0.05 are marked with different letters. C, CPD levels in the DNA of wild-type Col-0 and PDCD5 OE plants (PDCD5 OE-2, PDCD5 OE-11, and PDCD5 OE-12) immediately after a 4-h UV-B treatment. CPD levels are indicated as integrated optical density (IOD) values. Results represent averages ± se of three independent biological replicates. Statistical significance was analyzed using a one-way ANOVA test at P < 0.05; differences from the control are marked with different letters.