Distribution of OT and LT at the pre-specified time points. LT, lysis time; OT, occlusion time. *P < 0.01 compared to baseline. OT at baseline vs. discharge (paired t-test: mean difference 92 s, 95% CI 66.61–117.57; P < 0.001). OT at baseline vs. 30 days (Mann–Whitney U test: mean difference 193 s, 95% CI 158.29–229.61; P < 0.001).