Allele frequencies for L41F and R42H in all tested amplicon panel samples. Each column is a sample, the tissues represented by colour; blood (BL, blue), cerebellum (CER, green), dentate gyrus (DG, red), hippocampus (HIP, orange), middle temporal gyrus (MTG, purple), middle frontal gyrus (MFG, salmon) and superior parietal lobe (LPS, pink). The vertical axis shows the variant allele frequency in that respective tissue, with lines representing the 0.25% and 0.50% thresholds. The tissues with highest variant allele frequency are labelled with the patient identifier and respective tissue.