Figure 7.
Model: Suppression of the Arabidopsis Immune Response by COR.
Unknown elicitors from Pto (PAMPs and/or T3Es) activate SA signaling and indole glucosinolate metabolism. SA signaling and JA signaling are antagonistic, with COR activating COI1 to suppress SA accumulation. COR also suppresses indole glucosinolate metabolism upstream of 4MI3G accumulation. SA signaling promotes indole glucosinolate metabolism, perhaps by suppressing JA accumulation, and also promotes callose deposition independent of COI1 through an unknown pathway. COR suppresses defense in a COI1-independent manner through an unknown pathway.