Risk of cardiovascular disease associated with calcium status and per 0.1 mmol/L higher plasma ionized calcium, stratified by median plasma ionized calcium. Analyses are multivariable adjusted for year and month of measurement, sex, body mass index, alcohol intake, smoking status, use of diuretics, income, physical activity during leisure time, systolic blood pressure, estimated glomerular filtration rate, plasma non-HDL cholesterol, any use of vitamins, hypertension, chronic illnesses, and diabetes, and age is used as time scale. Estimates adjusted for regression dilution bias. N: total number of individuals. Analyses per 0.1 mmol/L higher plasma ionized calcium were stratified by the median of 1.21 mmol/L.