Control of the concentration of transcripts for enzymes involved in central carbon metabolism. Ratios of mRNA concentrations (white bar) and mRNA half-lives (grey bar) are represented for the three growth rate comparisons (left to right: 0.20 versus 0.10 h−1, 0.40 versus 0.20 h−1 and 0.63 versus 0.40 h−1) for 34 genes encoding enzymes of the central carbon metabolism. Growth rate comparisons for which the mRNA concentration is controlled mainly by degradation (ρD classes IV and V) are colored in red. The pathway names are given in boxes (PP: pentose phosphate pathway, ED: Entner–Doudoroff pathway, TCA: tricarboxylic acid cycle) and the direction of flow are indicated by arrows. Metabolites, GLC: glucose, PEP: phosphoenolpyruvate, 6PG: 6-phosphogluconate, PYR: pyruvate, OAA: oxaloacetate, AcCoA: acetyl-CoA and ACE: acetate. Enzymes, galM: galactose-1-epimerase, ptsH/ptsI/crr: PTS system, pgm: phosphoglucomutase, zwf: glucose 6-phosphate-1-dehydrogenase, fbaA: fructose bisphosphate aldolase, gapA: glyceraldehyde 3-phosphate dehydrogenase, pgk: phosphoglycerate kinase, gpmA: 2,3–bisphosphoglycerate-dependent phosphoglycerate mutase, gpmM: 2,3–bisphosphoglycerate-independent phosphoglycerate mutase, edd: phosphogluconate dehydratase, eda: Entner-Doudoroff aldolase, ppc: PEP carboxylase, pck: PEP carboxykinase, ppsA: PEP synthetase, lpd/aceF: pyruvate dehydrogenase, ackA: acetate kinase, acs: acetyl-CoA synthetase, gltA: citrate synthase, acnB: aconitase B, icd: isocitrate dehydrogenase, aceK: isocitrate dehydrogenase kinase/phosphatase, sdhA/B/C/D: succinate dehydrogenase, frdA/B: fumarate reductase, fumC: fumarase C, mqo: malate:quinone oxidoreductase and maeA/maeB: malic enzymes.
