Association between age at examination, disease duration and IL6 release. (A) In patients with idiopathic Parkinson’s disease (n = 51), we observed elevated IL6 levels with increasing age when determining the Spearman’s correlation of both variables. (B) In PRKN/PINK1 biallelic and heterozygous patients (n = 31), there was a positive correlation between disease duration and IL6 levels. The Spearman’s correlation was calculated after adjusting for age at examination. Correlation coefficient is shown in the top left, exploratory P-values are presented in the top right corner. Lines represent linear regression.