Thresholds for 12 biomarker genes. The threshold values for the 12 biomarker genes derived from 4 datasets are shown. All thresholds were derived using the highest value in the nontumorigenic group with outliers removed. All fold-change values were derived from analysis in BaseSpace Correlation Engine (Method 1) except the Method 2 group, which derived the fold-changes using the R procedures as described in the Materials and Methods section. Numbers above the bars indicate the number of outliers removed from the derivation of the thresholds. Abbreviations: AhR, aryl hydrocarbon receptor; CAR, constitutive activated receptor; ER, estrogen receptor; PPARα, peroxisome proliferator-activated receptor α.