Intrinsic connectivity networks and between-network analysis. (A) Spatial maps of the 13 independent components computed for the entire sample (31 ischaemic stroke patients and 17 healthy controls). These maps were organized in three domains: sensorimotor (SMN, eight components, framed in dark blue), subcortical (SC, three components, framed in light blue) and cerebellar (CB, two components, framed in orange). Components were back-reconstructed based on the independent components of the cortical and subcortical sensorimotor as well as cerebellar domains presented in Allen et al. (2014). (B) Static functional network connectivity between independent components resulting in a total of 78 connectivity pairs. Connectivity values correspond to the Fisher’s Z-transformed Pearson correlation, averaged over the entire group of healthy controls and ischaemic stroke patients. Red colour indicates positive correlation, blue colour indicates negative correlation. Thus, the connectivity matrix illustrates high positive intra-domain connectivity within the sensorimotor, subcortical and cerebellar domains as well as neutral to negative inter-domain connectivity: SMN-SC, SMN-CB and SC-CB. Asterisks indicate significantly altered static connectivity between the three subgroups: healthy controls, moderately, and severely affected stroke patients (one-way ANOVA, P < 0.05). The components ‘left ipsilesional sensorimotor’ and ‘bilateral postcentral gyri’ were both characterized by the highest number of disturbed static connectivity pairs (six each). L = left; R = right; SMA = supplementary motor area.