Distance distribution between the drug center and atoms on the 3-dimensional interaction surface of target P36888 (protein receptor-type tyrosine-protein kinase FLT3). |$r$| and |$p$| indicate similarity score and statistical significance of drug pairs, respectively. (A–E) presents two drugs with an identical target and similar efficacy (above threshold r > 0.7, P < 0.05). (F–N) presents two drugs with an identical target and a non-similar efficacy (below threshold).