Myopia genetic risk score effect on RD risk using UK Biobank RD-SR-ICD cases or clinically ascertained RRD cases. The effects of consecutive myopia genetic risk score (GRS) quintile on RD (RD-SR-ICD) risk in UK Biobank and on RRD risk in the aggregated clinically ascertained sets are displayed in black and grey bars, respectively. Quintiles were calculated using N = 408 972 UK Biobank participants of white-British ancestry. OR for detachment, plotted along the y-axis, uses odd in the first quintile as the reference. GRS boundaries for each quintile are given in Figure S6. Error bars denote the OR 95% CI.