Fluorouracil treatment of MAF-928_XC. (A) Sagittal plane, T2 scans at 4 and 8 weeks post initiation of 5FU treatment. Mice received either vehicle or 30 mg/kg 5FU i.p. once weekly for 7 total doses. Blue arrow indicates posterior fossa disease; yellow arrow indicates metastases. (B) Quantification of tumor volume at each scan time. Blue denotes vehicle treated mice; red denotes 5FU treated mice. (C) Survival time of vehicle (blue), 5FU (red) treated mice.