Forest plots for (A) thrombolysis in myocardial infarction major bleeding and (B) thrombolysis in myocardial infarction major in combination with thrombolysis in myocardial infarction minor bleeding are shown with standard errors of the treatment effect and calculated hazard ratio with corresponding 95% confidence interval. In (B), the PIONEER AF-PCI trial also included trial-defined clinically significant bleeding in the analysis. CI, confidence interval; DAT, dual antithrombotic therapy; HR, hazard ratio; IV, inverse variance; SE, standard error; TAT, triple antithrombotic therapy; TE, treatment effect; TIMI, thrombolysis in myocardial infarction.