Figure 1
![Epac1 expression during VTP time course. (A, B) Epac1 mRNA expression in isolated atrial and ventricular canine fibroblasts (FBs), respectively, during VTP [*P < 0.05, **P < 0.01, ***P < 0.001 vs. control (CTL), one-way ANOVA followed by Dunnett’s multiple comparison test]. (C) Freshly isolated left-atrial and ventricular fibroblasts were obtained from CTL and 2-week VTP (CHF) dogs. Top Immunoblots for Epac1 protein-expression. Bottom Epac1 protein-expression relative to GAPDH (*P < 0.01, **P < 0.001, ***P < 0.0001, two-way ANOVA followed by the Tukey’s test). Each dot represents an individual animal.](https://oup.silverchair-cdn.com/oup/backfile/Content_public/Journal/cardiovascres/115/1/10.1093_cvr_cvy173/3/cvy173f1.jpeg?Expires=1750780365&Signature=a7xPa9rkM4ykUiboC3y9G6sJNluYKotKrGrTa8j5B1c9EPvwiv03q4I8y6GEaxCV597-clrNo8j4MF6LVhPUeMZDD9jmEWqNB029TemY3KMtuETSz-nD3t0HBK74hMil7mPpILjUwljaEJVKggLGpn~jh5PbDsd0MZtMIk2MucLFmDs0YCYsNfoOTNNDcSaICHpg~vPigYiRz2V7zQXEC9cVLkVKYY--xYzmdCA~pvyu84xiOToQdjCJNKDwxi1hiO1pde24Ka7Mjdr8XenR1QVMSmt1P1Q9Z-OlEZb8e5fBw8raJqZeHHaTfVVkC2YjKJtYRHK8Re8gkhNVka2S5w__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Epac1 expression during VTP time course. (A, B) Epac1 mRNA expression in isolated atrial and ventricular canine fibroblasts (FBs), respectively, during VTP [*P < 0.05, **P < 0.01, ***P < 0.001 vs. control (CTL), one-way ANOVA followed by Dunnett’s multiple comparison test]. (C) Freshly isolated left-atrial and ventricular fibroblasts were obtained from CTL and 2-week VTP (CHF) dogs. Top Immunoblots for Epac1 protein-expression. Bottom Epac1 protein-expression relative to GAPDH (*P < 0.01, **P < 0.001, ***P < 0.0001, two-way ANOVA followed by the Tukey’s test). Each dot represents an individual animal.
