Frequency and segregation of the 4q25 loci rs2200733 and rs13143308. (A) The frequency of the rs2200733T (rs..733T) and rs13143308T (rs..308T) risk variants on chromosome 4q25. Number of patients genotyped are given for each risk variant in patients without (No AF) and with AF. (B) Relative frequency of rs..733 and rs..308 genotypes in 342 patients donating right atrial tissue (black bars). T at rs..733 indicates the presence of at least one risk allele, and T at rs..308 indicates the presence of at least one risk allele at this locus. Grey bars indicate the expected frequency of the same genotypes based on the allele frequencies. P-value for difference between observed and expected frequencies are given on the right.