Comparisons of Task and Rest. (A) Group differences in region-by-region functional connectivity during task in task-defined regions. Higher values indicate larger Autism > Control differences. (B) Group differences in region-by-region functional connectivity in resting state data, measured in the same task-defined regions. (C) Green squares and lines indicate pairs of regions with Autism > Control differences that replicate across Task and Rest. These ‘core’ effects involved the left thalamus and the right ventral striatum (corrected by FDR to q < 0.05 in both Task and Rest). Black squares and lines indicate ‘contextual’ effects occurring between cortical areas (significant Group × State interaction, corrected by FDR to q < 0.05).