Oocyte maturation and reactive oxygen species (ROS) production in oocytes from corticosterone (CORT)-treated mice. (A) The in IVM maturation rate from CORT-treated mice (n = 196) and vehicle-treated mice (n = 120). (B) Histogram showing quantification of dichlorofluorescein (DCFH) fluorescence; there was no significant difference of ROS production compared to the vehicle-treated group (P > 0.05). (C) ROS production in germinal vesicle (GV) and metaphase 2 (MII) oocytes from CORT-treated mice and vehicle-treated mice.