(A) Domain (left) and boundary (right) TPR and FDR between the segmentations given by IC-Finder (taken as the reference) and the segmentations obtained by three other methods for Hi-C data from Mouse ES cells and Human IMR90 cell line (data from (2)). (B) For each method, domain (left) and boundary (right) TPR and FDR between the predicted segmentations of two biological replicates. Each symbol of the same color represents the TPR/FDR obtained in a given drosophila cell line (S2, KC, BG3 or OSC, data from (6)).